In the mid-20th century, Wilmington was a company town — everyone worked for DuPont. Today, the former DuPont headquarters, a 1913 Italian Renaissance high-rise, is the epicenter of a revitalized downtown. Part of the building is dedicated to Hotel du Pont, a restored grand dame with spacious rooms sporting city views. The hotel’s fabled Green Room, where movers and shakers dined for decades, has been transformed by Philadelphia chef Tyler Akin into Le Cavalier, a French brasserie with North African accents and an excellent natural wine list.